Human CGRPR Protein, hFc Tag

Description :Recombinant human CGRPR Protein with C-terminal human Fc tagBackground : Enables adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Located in endoplasmic reticulum; endosome; and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. Molecular Characterization: mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of CGRPR-hFc is approximately 35-70 kDa due to glycosylation.Tag :C-Human Fc tag

Product Specifications

Product Name Alternative

CRLR; CALCRL; LMPHM8

UniProt

Q16602

Host

HEK293

Target Antigen

CGRPR

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.