Human GDF8 Protein, hFc Tag
Description :Recombinant human GDF8 Protein with C-terminal human Fc tagBackground : This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. Molecular Characterization: mass of 66.2 kDa after removal of the signal peptide.Tag :C-Human Fc tag
Product Specifications
Product Name Alternative
MSTN; MSLHP
UniProt
O14793
Host
HEK293
Target Antigen
GDF8
Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Storage Conditions
Frequently Asked Questions
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