Human BCMA (22-42) Protein, mFc Tag

Description :Recombinant human BCMA (22-42) Protein with C-terminal mouse Fc tagBackground : B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF) . This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.Molecular Characterization: mass of 28.5 kDa after removal of the signal peptide. The apparent molecular mass of BCMA (22-42) -mFc is approximately 25-35 kDa due to glycosylation.Tag :C-mouse Fc tag

Product Specifications

Product Name Alternative

BCM; TNFRSF17; CD269

UniProt

Q02223

Host

HEK293

Target Antigen

BCMA

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.