Human LILRB5 Protein, His Tag

Description :Recombinant Human LILRB5 Protein with C-terminal6Ã-His tagBackground : This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) . Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. Molecular Characterization: mass of 48.1 kDa after removal of the signal peptide. The apparent molecular mass of LILRB5-His is approximately 55-70 kDa due to glycosylation.Tag :C-6Ãƒâ€”His Tag

Product Specifications

Product Name Alternative

LIR8; CD85C; LIR-8

UniProt

O75023

Host

HEK293

Target Antigen

LILRB5

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.