Human CCL11 Protein, hFc Tag

Description :Recombinant Human CCL11 Protein with C-terminal human Fc tagBackground : This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. Molecular Characterization: mass of 34.0 kDa after removal of the signal peptide. The apparent molecular mass of CCL11-hFc is approximately 35-55 kDa due to glycosylation.Tag :C-Human Fc Tag