Human DSG2 (50-609) Protein, His Tag

Description :Recombinant Human DSG2 (50-609) Protein with C-terminal 6XHis tag Background : This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. Molecular Characterization: mass of 63.3 kDa after removal of the signal peptide. The apparent molecular mass of DSG2 (50-609) -His is approximately 70-100 kDa due to glycosylation. Tag :C-6XHis Tag

Product Specifications

Product Name Alternative

CDHF5; HDGC

UniProt

Q14126

Host

HEK293

Target Antigen

DSG2

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.