Human ADAMTS13 Protein, His Tag
Description :Recombinant human ADAMTS13 protein with C-terminal 6XHis tag Background : This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF) . Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. Molecular Characterization: mass of 150.8 kDa after removal of the signal peptide. The apparent molecular mass of ADAMTS13-His is approximately 130-250 kDa due to glycosylation. Tag :C-6XHis tag
Product Specifications
Product Name Alternative
A disintegrin and metalloproteinase with thrombospondin motifs 13 ?ADAM-TS 13?ADAM-TS13?ADAMTS-13?vWF-CP? vWF-cleaving protease
UniProt
Q76LX8
Host
HEK293
Target Antigen
ADAMTS13
Purification
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
Storage Conditions
Frequently Asked Questions
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