Human CD3D Protein, His Tag and Human CD3E Protein, hFc Tag

Description :Recombinant Human CD3D Protein with C-terminal 6XHis tag and Human CD3E Protein with C-terminal human Fc tag Background : T-cell surface glycoprotein CD3 delta and CD3 epsilon chain, also known as CD3D and CD3E or CD3DandCD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Molecular Characterization: mass of 10.4 and 37.9 kDa after removal of the signal peptide. The apparent molecular mass of CD3D-His and CD3E-hFc is approximately 35-55 kDa due to glycosylation. Tag :C-6XHis Tag and C-Human Fc Tag

Product Specifications

Product Name Alternative

CD3-DELTA; IMD19; T3D and IMD18; T3E; TCRE

UniProt

P04234; P07766

Host

HEK293

Target Antigen

CD3D; CD3E

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.