Human MERTK Protein, His Tag

Description :Recombinant human MERTK Protein with C-terminal 10XHis tag Background : This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) . Molecular Characterization: mass of 54.0 kDa after removal of the signal peptide. Tag :C-10XHis Tag

Product Specifications

Product Name Alternative

MER; RP38; c-Eyk; c-mer; Tyro12

UniProt

Q12866

Host

HEK293

Target Antigen

MERTK

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.