Human KI67 (1206-1238) Protein, hFc Tag

Description :Recombinant human KI67 (1206-1238) Protein with C-terminal human Fc tag Background: Enables protein C-terminus binding activity. Involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Colocalizes with condensed chromosome. Implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple) ; endocrine gland cancer (multiple) ; gastrointestinal system cancer (multiple) ; and interstitial cystitis. [provided by Alliance of Genome Resources, Apr 2022] Description: Recombinant human KI67 (1206-1238) Protein with C-terminal human Fc tag Molecular Characterization: KI67 (Gly1206-Glu1238) hFc (Glu99-Ala330) Molecular Weight :The protein has a predicted molecular mass of 29.8 kDa after removal of the signal peptide. The apparent molecular mass of KI67 (1206-1238) -hFc is approximately 35-55 kDa due to glycosylation. Tag :C-Human Fc tag