Human KI67 (1206-1238) Protein, hFc Tag

Description :Recombinant human KI67 (1206-1238) Protein with C-terminal human Fc tag Background: Enables protein C-terminus binding activity. Involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Located in chromosome; nuclear body; and nucleolus. Colocalizes with condensed chromosome. Implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Biomarker of several diseases, including Barrett's esophagus; autoimmune disease of musculoskeletal system (multiple) ; endocrine gland cancer (multiple) ; gastrointestinal system cancer (multiple) ; and interstitial cystitis. [provided by Alliance of Genome Resources, Apr 2022] Description: Recombinant human KI67 (1206-1238) Protein with C-terminal human Fc tag Molecular Characterization: KI67 (Gly1206-Glu1238) hFc (Glu99-Ala330) Molecular Weight :The protein has a predicted molecular mass of 29.8 kDa after removal of the signal peptide. The apparent molecular mass of KI67 (1206-1238) -hFc is approximately 35-55 kDa due to glycosylation. Tag :C-Human Fc tag

Product Specifications

Product Name Alternative

KIA; MIB-; MIB-1; PPP1R105; MKI67

UniProt

P46013

Host

HEK293

Target Antigen

KI67

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.