Human CDH17 (567-667) Protein, hFc Tag

Description :Recombinant human CDH17 (567-667) Protein with C-terminal human Fc tag Background : This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. Molecular Characterization: mass of 37.0 kDa after removal of the signal peptide. The apparent molecular mass of CDH17 (567-667) -hFc is approximately 35-55 kDa due to glycosylation. Tag :C-Human Fc Tag

Product Specifications

Product Name Alternative

CDH16; HPT-1; HPT1

UniProt

Q12864

Host

HEK293

Target Antigen

CDH17

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.