Recombinant Human CD14 (20-352) Protein, His Tag

Molecular Characterization: CD14 (Thr20-Cys352) 7Ãƒâ€”His tagMolecular weight: The protein has a predicted molecular mass of 36.7 kDa after removal of the signal peptide. The apparent molecular mass of CD14 (20-352) -7xHis is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human CD14 (20-352) Protein with C-terminal 7Ãƒâ€”His tagThe protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein.

Product Specifications

Product Name Alternative

CD14 Molecule?Myeloid Cell-Specific Leucine-Rich Glycoprotein?CD14 Antigen?Monocyte Differentiation Antigen CD14

UniProt

P08571

Host

HEK293

Target Antigen

CD14

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.