Recombinant Human GPR56 Protein, His Tag

Molecular Characterization: GPR56 (Arg26-Tyr402) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 43.6 kDa after removal of the signal peptide. The apparent molecular mass of GPR56-His is approximately 55-70 kDa due to glycosylation.Description: Recombinant Human GPR56 Protein with C-terminal6Ã-His tagThis gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants.