Recombinant Human ANGPT2 (275-496) Protein, His Tag

Molecular Characterization: ANGPT2 (Lys275-Phe496) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 26.3 kDa after removal of the signal peptide. The apparent molecular mass of ANGPT2 (275-496) -His is approximately 25-35 kDa due to glycosylation.Description: Recombinant Human ANGPT2 (275-496) Protein with C-terminal6Ã-His tagThis gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.

Product Specifications

Product Name Alternative

AGPT2; ANG2; LMPHM10

UniProt

O15123

Host

HEK293

Target Antigen

ANGPT2

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.