Recombinant Human ANPRB Protein, His Tag

Molecular Characterization: ANPRB (Arg23-Ile458) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 49.3 kDa after removal of the signal peptide.Description: Recombinant Human ANPRB Protein with C-terminal6Ã-His tagThis gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Product Specifications

Product Name Alternative

AMDM; ANPb; NPR2; ECDM; GC-B; GCB; GUC2B; GUCY2B; NPRB; NPRBi; SNSK

UniProt

P20594

Host

HEK293

Target Antigen

ANPRB

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.