Recombinant Human CDH11 (23-617) Protein, His Tag

Molecular Characterization: CDH11 (23-617) (Phe23-Thr617) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 66.4 kDa after removal of the signal peptide. The apparent molecular mass of CDH11 (23-617) -His is approximately 70-100 kDa due to glycosylation.Description: Recombinant Human CDH11 (23-617) Protein with C-terminal6Ã-His tagThis gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Product Specifications

Product Name Alternative

CAD11; CDHOB; ESWS; OB; OSF-4

UniProt

P55287

Host

HEK293

Target Antigen

CDH11

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.