Recombinant Human POSTN Protein, His Tag

Molecular Characterization: POSTN (Asn22-Gln836) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 91.8 kDa after removal of the signal peptide. The apparent molecular mass of POSTN-His is approximately 55-100 kDa due to glycosylation.Description: Recombinant Human POSTN Protein with C-terminal6Ã-His tagThis gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Specifications

Product Name Alternative

OSF-2; OSF2; PDLPOSTN; PN

UniProt

Q15063

Host

HEK293

Target Antigen

POSTN

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.