Recombinant Human IGF-I (67AA) Protein

Molecular weight: 7.3 KDaDescription: Recombinant Human Insulin-like Growth Factor I (4-70) is produced by our E.coli and the target gene encoding Thr52-Ala118 is expressed.Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.

Product Specifications

Product Name Alternative

Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

UniProt

P05019

Host

E.coli

Target Antigen

IGF-I

Components

Lyophilized from a 0.2 ?m filtered solution of 20mM NaAc-HAc, pH 4.5

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.