Recombinant Human IRF5 (C-6His) Protein

Molecular weight: 57.1 KDaDescription: Recombinant Human Interferon Regulatory Factor 5 is produced by our E.coli and the target gene encoding Met1-Gln498 is expressed with a 6His tag at the C-terminus.Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.

Product Specifications

Product Name Alternative

Interferon Regulatory Factor 5; IRF-5; IRF5

UniProt

Q13568

Host

E.coli

Target Antigen

IRF5

Components

Supplied as a 0.2 ?m filtered solution of 20mM Tris-HCl, 150mM NaCl, 30% Glycerol, 1mM DTT, pH 8.0.

Storage Conditions

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.