Recombinant Human BTN3A3 Protein, His Tag

Molecular Characterization: BTN3A3 (Gln30-Trp248) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 24.4 kDa after removal of the signal peptide. The apparent molecular mass of BTN3A3-His is approximately 25-35 kDa due to glycosylation.Description: Recombinant human BTN3A3 protein with C-terminal6Ã-His tagThe butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC) -associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]) .[supplied by OMIM, Nov 2010]

Product Specifications

Product Name Alternative

BTF3

UniProt

O00478

Host

HEK293

Target Antigen

BTN3A3

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.