Recombinant Mouse BAFF Protein, hFc Tag

Molecular Characterization: hFc (Glu99-Ala330) Mouse BAFF (Ala127-Leu309) Molecular weight: The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mBAFF is approximately 40-55 kDa due to glycosylation.Description: Recombinant mouse BAFF protein with N-terminal human Fc tagCytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.[UniProtKB/Swiss-Prot Function]

Product Specifications

Product Name Alternative

B-cell-activating factor, CD257, Tnfsf13b, Baff

UniProt

Q9WU72

Host

HEK293

Target Antigen

BAFF

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.