Recombinant Mouse ROR1 Protein, His Tag

Molecular Characterization: Mouse ROR1 (Gln30-Glu403) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 42.6 kDa after removal of the signal peptide. The apparent molecular mass of mROR1-His is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse ROR1 protein with C-terminal6Ã-His tagThis gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Specifications

Product Name Alternative

Ror1

UniProt

Q9Z139

Host

HEK293

Target Antigen

ROR1

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.