Recombinant Mouse TACI Protein, hFc Tag

Molecular Characterization: Mouse TACI (Met1-Thr125) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 40.2 kDa after removal of the signal peptide. The apparent molecular mass of mTACI-hFc is approximately 40-55 kDa due to glycosylation.Description: Recombinant mouse TACI protein with C-terminal human Fc tagReceptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity (By similarity) .[UniProtKB/Swiss-Prot Function]