Recombinant Human TREM1 Protein, hFc Tag

Molecular Characterization: TREM1 (Ala21-Arg200) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 46.4 kDa after removal of the signal peptide. The apparent molecular mass of TREM1-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant human TREM1 protein with C-terminal human Fc tagThis gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Product Specifications

Product Name Alternative

TREM-1, CD354

UniProt

Q9NP99

Host

HEK293

Target Antigen

TREM1

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.