Recombinant Mouse CB1 Protein, hFc Tag

Molecular Characterization: Mouse CB1 (Met1-Leu118) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 39.4 kDa after removal of the signal peptide. The apparent molecular mass of mCB1-hFc is approximately 40-55 kDa due to glycosylation.Description: Recombinant mouse CB1 protein with C-terminal human Fc tagThis gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

Product Specifications

Product Name Alternative

Cannabinoid receptor 1, CB-R, Cnr1

UniProt

P47746

Host

HEK293

Target Antigen

CB1

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.