Recombinant Mouse CD200 Protein, hFc Tag

Molecular Characterization: Mouse CD200 (Gln31-Gly232) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 48.7 kDa after removal of the signal peptide. The apparent molecular mass of mCD200-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse CD200 protein with C-terminal human Fc tagThis gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Specifications

Product Name Alternative

MRC OX-2 antigen, Mox2

UniProt

O54901

Host

HEK293

Target Antigen

CD200

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.