Recombinant Mouse CD200 Protein, hFc Tag

Molecular Characterization: Mouse CD200 (Gln31-Gly232) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 48.7 kDa after removal of the signal peptide. The apparent molecular mass of mCD200-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse CD200 protein with C-terminal human Fc tagThis gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.