Recombinant Mouse B7-1 Protein, hFc Tag

Molecular Characterization: Mouse B7-1 (Val38-Lys245) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 49.8 kDa after removal of the signal peptide. The apparent molecular mass of mB7-1-hFc is approximately 70-100 kDa due to glycosylation.Description: Recombinant mouse B7-1 protein with C-terminal human Fc tagThe protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.

Product Specifications

Product Name Alternative

B7, CD80

UniProt

Q00609

Host

HEK293

Target Antigen

B7-1

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.