Recombinant Human TIMP4 Protein, hFc Tag

Molecular Characterization: TIMP4 (Cys30-Pro224) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 48.6 kDa after removal of the signal peptide. The apparent molecular mass of TIMP4-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant human TIMP4 protein with C-terminal human Fc tagThis gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

Product Specifications

Product Name Alternative

TIMP-4

UniProt

Q99727

Host

HEK293

Target Antigen

TIMP4

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.