Recombinant Human TIMP4 Protein, hFc Tag

Molecular Characterization: TIMP4 (Cys30-Pro224) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 48.6 kDa after removal of the signal peptide. The apparent molecular mass of TIMP4-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant human TIMP4 protein with C-terminal human Fc tagThis gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.