Recombinant Human IL17RB Protein, His Tag

Molecular Characterization: IL17RB (Arg18-Gly288) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 30.7 kDa after removal of the signal peptide. The apparent molecular mass of TEM1 -His is approximately 35-55 kDa due to glycosylation.Description: Recombinant human IL17RB protein with C-terminal6Ã-His tagThe protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Product Specifications

Product Name Alternative

Interleukin-17 receptor B, IL-17 receptor B, IL-17RB, Cytokine receptor-like 4, IL-17Rh1, IL17Rh1, IL-17B receptor

UniProt

Q9NRM6

Host

HEK293

Target Antigen

IL17RB

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.