Recombinant Canis lupus familiaris ANXA2 Protein, His Tag

Molecular Characterization: ANXA2 (Ser2-Asp339) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide. The apparent molecular mass of dANXA2-His is approximately 35-55 kDa due to glycosylation.Description: Recombinant canis ANXA2 protein with C-terminal6Ã-His tagThis gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.

Product Specifications

Product Name Alternative

Annexin A2, Annexin-2

UniProt

Q6TEQ7

Host

HEK293

Target Antigen

ANXA2

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.