Recombinant Human ADGRE2 Protein, His Tag

Molecular Characterization: ADGRE2 (Gln24-Thr537) 7Ãƒâ€”His tagMolecular weight: The protein has a predicted molecular mass of 57.2 kDa after removal of the signal peptide. The apparent molecular mass of ADGRE2-His is approximately 70-100 kDa due to glycosylation.Description: Recombinant human ADGRE2 protein with C-terminal 7Ãƒâ€”His tagThis gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Specifications

Product Name Alternative

Adhesion G protein-coupled receptor E2?EGF-like module receptor 2?EGF-like module-containing mucin-like hormone receptor-like 2?CD312

UniProt

Q9UHX3

Host

HEK293

Target Antigen

ADGRE2

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.