Recombinant Human ADAM8 Protein, His Tag

Molecular Characterization: ADAM8 (Ile17-Pro655) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 70.6 kDa after removal of the signal peptide. The apparent molecular mass of ADAM8-His is approximately 55-70 kDa and 70-100 kDa due to glycosylation.Description: Recombinant human ADAM8 protein with C-terminal6Ã-His tagThis gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

Product Specifications

Product Name Alternative

Cell surface antigen MS2?CD156a

UniProt

P78325

Host

HEK293

Target Antigen

ADAM8

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.