Recombinant Cynomolgus CXCL4 Protein, hFc Tag

Molecular Characterization: CXCL4 (Glu34-Ser101) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 33.7 kDa after removal of the signal peptide. The apparent molecular mass of cCXCL4-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Cynomolgus CXCL4 protein with C-terminal human Fc tagThis gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.

Product Specifications

Product Name Alternative

PF-4, Iroplact, Oncostatin-A

UniProt

P02776

Host

HEK293

Target Antigen

CXCL4

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.