Recombinant Human ITGB1 Protein, hFc Tag

Molecular Characterization: ITGB1 (Gln21-Asp728) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 104.5 kDa after removal of the signal peptide. The apparent molecular mass of ITGB1-hFc is approximately 130-250 kDa due to glycosylation.Description: Recombinant human ITGB1 protein with C-terminal human Fc tagIntegrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Product Specifications

Product Name Alternative

GPIIA, CD29, VLA-4 subunit beta

UniProt

P05556

Host

HEK293

Target Antigen

ITGB1

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.