Recombinant Mouse MFGE8 Protein, His Tag

Molecular Characterization: Mouse MFGE8 (Ala23-Cys463) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 49.8 kDa after removal of the signal peptide.The apparent molecular mass of mMFGE8-His is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse MFGE8 protein with C-terminal6Ã-His tagContributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction (By similarity) . Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization.[UniProtKB/Swiss-Prot Function]

Product Specifications

Product Name Alternative

MFGM; SED1; MP47, MFG-E8

UniProt

P21956

Host

HEK293

Target Antigen

MFGE8

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.