Recombinant Mouse GITR Protein, hFc Tag

Molecular Characterization: Mouse GITR (Ser22-His153) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 40.3 kDa after removal of the signal peptide.The apparent molecular mass of mGITR-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant mouse GITR protein with C-terminal human Fc tagReceptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity) .[UniProtKB/Swiss-Prot Function]

Product Specifications

Product Name Alternative

AITR; Gitr

UniProt

O35714

Host

HEK293

Target Antigen

GITR

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.