Recombinant Mouse CD28 Protein, hFc Tag

Molecular Characterization: Mouse CD28 (Asn20-Lys149) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 41.2 kDa after removal of the signal peptide.The apparent molecular mass of mCD28-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse CD28 protein with C-terminal human Fc tagInvolved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.[UniProtKB/Swiss-Prot Function]