Recombinant Mouse CD28 Protein, hFc Tag

Molecular Characterization: Mouse CD28 (Asn20-Lys149) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 41.2 kDa after removal of the signal peptide.The apparent molecular mass of mCD28-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse CD28 protein with C-terminal human Fc tagInvolved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.[UniProtKB/Swiss-Prot Function]

Product Specifications

Product Name Alternative

CD28, Tp44

UniProt

P31041

Host

HEK293

Target Antigen

CD28

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.