Recombinant Mouse B7-H3 Protein, hFc Tag

Molecular Characterization: Mouse B7-H3 (Val29-Phe244) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 28.7 kDa after removal of the signal peptide.The apparent molecular mass of mB7-H3-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse B7-H3 protein with C-terminal human Fc tagModulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells.[UniProtKB/Swiss-Prot Function]

Product Specifications

Product Name Alternative

6030411F23Rik; AU016588; B7h3; B7RP-2

UniProt

Q8VE98

Host

HEK293

Target Antigen

B7-H3

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.