Recombinant Mouse B7-H3 Protein, hFc Tag

Molecular Characterization: Mouse B7-H3 (Val29-Phe244) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 28.7 kDa after removal of the signal peptide.The apparent molecular mass of mB7-H3-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse B7-H3 protein with C-terminal human Fc tagModulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells.[UniProtKB/Swiss-Prot Function]