Recombinant Human EVA1C Protein, hFc Tag

Molecular Characterization: EVA1C (Leu49-Glu320) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 56.6 kDa after removal of the signal peptide. The apparent molecular mass of EVA1C-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant Human EVA1C with C-terminal human Fc tagEVA1C (aliases C21orf63), first identified in 2001, is a membrane protein encoding-gene. EVA1C protein has been found in a variety of human tissues. Kanae Mitsunaga identified EVA1C protein possessing two repeats of putative ‘galactose-binding lectin domains’ that bind heparin. Although the role of EVA1C has not been reported in tumor, Manas Kotepui et al. reported that ADGRL3 (LPHN3), an important paralog of EVA1C gene, was upregulated in breast cancer and was correlated with axillary lymph node metastasis.