Recombinant Human EREG Protein, hFc Tag

Molecular Characterization: EREG (Val63-Leu108) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of EREG-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human EREG with C-terminal human Fc tagThis gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4) . The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.

Product Specifications

Product Name Alternative

Ep, EPR, ER

UniProt

O14944

Host

HEK293

Target Antigen

EREG

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.