Recombinant Human DLL3 Protein, hFc Tag

Molecular Characterization: DLL3 (Ala27-Arg490) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 74.4 kDa after removal of the signal peptide. The apparent molecular mass of DLL3-hFc is approximately 100-130 kDa due to glycosylation.Description: Recombinant human DLL3 protein with C-terminal human Fc tagThis gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.