Recombinant Human CD62L Protein, His Tag

Molecular Characterization: CD62L (Trp39-Asn332) 6Ã-His TagMolecular weight: The protein has a predicted molecular mass of 33.9 kDa after removal of the signal peptide.The apparent molecular mass of CD62L-His is approximately 35-70 kDa due to glycosylation.Description: Recombinant Human CD62L Protein with C-terminal6Ã-His tagThis gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Product Specifications

Product Name Alternative

CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1

UniProt

P14151

Host

HEK293

Target Antigen

CD62L

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.