Recombinant Human IL11RA Protein, hFc Tag

Molecular Characterization: IL11RA (Ser24-Ala370) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of IL11RA-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human IL11RA with C-terminal human Fc tagInterleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.

Product Specifications

Product Name Alternative

IL-11 R alpha, IL-11 RA, IL11RA, Interleukin-11 receptor subunit alpha, IL-11 receptor subunit alpha, IL-11R subunit alpha, IL-11R-alpha

UniProt

Q14626

Host

HEK293

Target Antigen

IL11RA

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.