Recombinant Human YAP1 Protein, His Tag

Molecular Characterization: YAP1 (Met1-Leu504) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 55.3 kDa after removal of the signal peptide.Description: Recombinant human YAP1 protein with C-terminal6Ã-His tagThis gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Specifications

Product Name Alternative

COB1, YAP, YAP2, YAP65, YKI

UniProt

P46937

Host

HEK293

Target Antigen

YAP1

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.