Recombinant Human CLEC14A Protein, His Tag

Molecular Characterization: CLEC14A (Glu22-Ala397) 6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 40.7 kDa after removal of the signal peptide. The apparent molecular mass of CLEC14A-His is approximately 70-100 kDa due to glycosylation.Description: Recombinant human CLEC14A protein with C-terminal6Ã-His tagThis gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting.