Human EDA Protein, hFc Tag

The protein has a predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-EDA is approximately 55-70 kDa due to glycosylation.The apparent molecular mass of GPR87-hFc is approximately 35-55 kDa due to glycosylation. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.

Product Specifications

Product Name Alternative

ED1; EDA2

Host

HEK293

Target Antigen

EDA

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) .Lyophilized proteins are shipped at ambient temperature.